Brandon Aiyuk

Brandon Aiyuk

WR - SF
Height: 6-1
Weight: 206 lbs
Age: 27
College: Arizona State
San Francisco 49ers

2025 Season Outlooks

Brandon Aiyuk is expected to return by Week 6.

Aiyuk will get drafted to Fantasy benches with a pick in the double-digit rounds this year after tearing both the ACL and MCL in his right knee last October. Reports in May suggest he'll begin the year on the Physically Unable to Perform list, canceling his availability through at least the Niners' first four games. It would make sense for the 49ers to not rush Aiyuk back, especially since they just gave him a fat new contract a year ago. That means all expectations for him are out the window, making him a potentially useless Fantasy pick. If your league has IR spots, you could conceivably draft Aiyuk and put him on IR while waiting to see what becomes of him in 2025, but it could prove to be a total waste.

Aiyuk is back in San Francisco for his sixth NFL campaign, but he's expected to miss roughly half of the season after suffering a torn ACL and MCL in October. Aiyuk had just received a contract extension, which followed back-to-back top-15 fantasy seasons, including a 2023 campaign in which he produced a career-high 1,342 yards (seventh among WRs) and ranked top 5 at the position in yards per reception, yards per target and yards per route run. Even prior to the injury, however, Aiyuk was underperforming last season, scoring zero TDs and reaching double-digit fantasy points once in seven games. Aiyuk is still in his prime at age 27, but it's unclear when he'll return, how effective he'll be, and how much work he'll be given in a fairly crowded offense. Aiyuk is only worth late-round consideration in deep leagues.

2025 Fantasy Football Rankings

Standard

#139

PPR

#146

Half-PPR

#136

Superflex

#152

2025 Fantasy Football Draft Projections

Rush Yds Rush TD Rec Rec Yds Rec TD
43.3 630.6 3.5

2025 Average Draft Position (ADP)

Standard

#120

Pick 10.12

PPR

#141

Pick 12.09

Half-PPR

#144

Pick 12.12

Superflex

#144

Pick 12.12

Injury Risk

Injury Risk:
Medium

Depth Chart

Depth Chart Not Available

Strength of Schedule

Average/Tough Season Ahead
1
2
3
4
5
6
7
8
9
10
11
12
13
Fantasy Playoffs
15
16
17
18