Perine is expected to serve as both the Bengals primary third-down back and as the main backup to Joe Mixon. He has not achieved over 500 yards in any of his past four seasons and has seven career touchdowns. Perine also had just two games with over 10 PPR points in 2021. Surely, the only reason to have Perine on a Fantasy bench is if you're in a very deep league and you want to have Mixon's backup ready to go in case of an injury. Expect to draft Perine with your last pick if you want him.
Cincinnati committed more to Joe Mixon on the ground throughout last season than it had previously under HC Zac Taylor, and Mixon’s receiving work picked up late in the year. There’s likely not enough room for another RB to be worth a fantasy look in any format as long as Mixon’s healthy. And it’s not clear heading into camp that Perine would assume lead-back touches even if Mixon goes down. Even on a handcuff level, you can find better late-draft RB options.
Perine is back with Cincinnati as the favorite for primary backup duties behind Joe Mixon. He's played that role the last two seasons, which has allowed rushing lines of 63-301-3 and 55-246-1, as well as receiving lines of 11-66-0 and 27-196-1. Perine's efficiency has been solid in recent years, but he has yet to produce a top-40 fantasy campaign in his five-year career. He can be expected to see a handful of touches each game this season and, should Mixon miss time, he'd lead a committee that would also include passing-down specialist Chris Evans. Perine is worth holding only if you roster Mixon in a very deep league.
Samaje Perine served as a clear handcuff and compliment to Mixon in 2021, playing roughly 20% of the snaps. His real value is in the passing game; he averaged close to two targets per game while Mixon only averaged three. If Mixon misses time, games like week 16 in 2020 with 136 total yards and two touchdowns show Perine has a usable fantasy ceiling.