Trey Sermon

49ers RB Elijah Mitchell (shoulder) is not listed on the final injury report. He practiced all week, including a full workout on Friday. Mitchell was operating as San Francisco's lead back before the Week 2 shoulder injury. RB Trey Sermon has been decent in his place the last 2 weeks, so it's unclear exactly how work will be divvied in Sunday's game vs. the Cardinals. Our guess is that Mitchell takes back over the lead role, but both he and Sermon look like risk/reward RB3 plays unless we hear more before kickoff.

Trey Sermon will get his second straight start for the 49ers.

49ers RB Elijah Mitchell (shoulder) is inactive for today s game vs. the Seahawks. That should again leave RB Trey Sermon in a lead -- but not featured -- role. The rookie played 59% of San Francisco's offensive snaps and tallied 10 carries and 3 targets last week. We re projecting similar usage today.

Missed practice Wednesday and Thursday 49ers TE George Kittle, listed as questionable for Sunday due to a calf injury, will play vs. the Seahawks, per source. 49ers RB Elijah Mitchell, listed as questionable for Sunday due to a shoulder injury, will be out Sunday vs. the Seahawks, per source. (Adam Schefter on Twitter) FF Today's Take: Kittle was limited in practice Friday but should be good to go this afternoon against Seattle. He's yet to find the endzone in 2021 but did have 9 targets last week (7-92) against the Packers. With Mitchell being out, Trey Sermon should see the bulk of running back touches but it's difficult to project him as anything more than a low-end RB2 given his low usage last week in the same role.

Rookie running back Trey Sermon had a much better week of practice as the 49ers prepare to face the Seahawks in Week 4.